Evolution of symbiotic bacteria in the distal human intestine


Jian Xu1,2*, Michael A. Mahowald1*, Ruth E. Ley1, Catherine A. Lozupone3, Micah Hamady4,  Eric C. Martens1, Bernard Henrissat5, Pedro M. Coutinho4, Patrick Minx2, Philippe Latreille2, Holland Cordum2, Andrew Van Brunt2, Kyung Kim2, Robert S. Fulton2, Lucinda A. Fulton2, Sandra W. Clifton2, Richard K. Wilson1,2, Robin D. Knight6, and Jeffrey I. Gordon1,2


1Center for Genome Sciences and 2Genome Sequencing Center, Washington University School of Medicine, St. Louis, MO 63108, 3Department of Molecular, Cellular and Developmental Biology and 4Department of Computer Science, University of Colorado, Boulder, CO 80309, 5CNRS-UMR6098, Universitˇs Aix-Marseille I & II, Marseille, France, and 6Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309


*Contributed equally


Additional files:


Gene Ontology hierarchy file used in the study (zip file)

Raw output from InterProScan (zip archive of tab delimited text files)

Complete lists of numbers of genes assigned to each GO term (zip archive of tab delimited text files)

Parsed list of InterPro ID, InterProScan hits and GO term assignments for each genome (zip archive of tab delimited text files)

Figure 5A with locus tags and bootstrap values (PDF)

Table of SusC/SusD homologs (xls file)

Table of SusC/SusD-linked genes (xls file)

The complete classification of the origin of all protein-coding genes in the gut Bacteroidetes and Porphyromonas gingivalis (xls file)